7. Computer simulation of pyramidal neurons in the cerebral cortex. Michael Häusser and colleagues developed the TREES toolbox based on the quantitative description of neuronal branching from neuroanatomist Ramón y Cajal. It allows automatic reconstruction of neuronal branching from microscopy image stacks. The visualized neurons can then be manipulated and analyzed in ways impossible with real neurons.
Cuntz, H., F. Forstner, A. Borst, M. Häusser.
"One rule to grow them all: a general theory of neuronal branching and its practical application."
PLoSComput Biol 2010, 5:e1000877